A heavy indica-dominant hybrid 70/30, it is a complex three-way cross of (Biscotti x Sherb BX1) x Jealousy. For medical marijuana patients, Permanent Marker provides deep, dual-action therapeutic relief. wipes away symptoms of chronic stress, severe depression, PTSD, and mood swings,highly effective for managing chronic pain, muscle spasms, and cramps without immediately knocking you out. Additionally, because it triggers a sharp increase in appetite, it is widely used by patients to combat nausea and appetite loss.